Certificate of participation with 1 CME is available
Necessitates Mechanical Debridement. However, achieving and maintaining therapeutic concentrations of antimicrobial or host-modulating agents precisely at the infected site—the periodontal pocket—presents a challenge that systemic antibiotics often fail to meet effectively due to dilution and associated side effects.
Key Focus
LDD systems directly address this challenge by providing sustained release of therapeutic agents, such as antibiotics (e.g., tetracycline, doxycycline, minocycline) or antiseptics (e.g., chlorhexidine), ensuring high local concentrations over an extended period. The lecture will categorize and detail various FDA-approved and emerging LDD systems, including:
Fibers and Strips: Non-resorbable matrix materials (e.g., Actisite).
Gels and Ointments: Bio-adhesive, site-specific formulations (e.g., Arestin, PerioChip).
Biodegradable Microspheres and Nanoparticles: Advanced systems offering tuneable release profiles.
Educational Outcomes
The pharmacokinetics of these local formulations will be compared to systemic administration, along with review of clinical evidence supporting their efficacy in reducing probing depth, improving clinical attachment levels, and managing refractory periodontitis. The advantages (reduced systemic load, enhanced patient compliance) and limitations (cost, application technique, localized resistance) of LDD, with a comprehensive understanding of when and how to integrate these valuable tools into modern, patient-centered periodontal care will be discusses.
Date:22/02/2026 |03:00 PM IST
